Reversal of oncogene transformation and suppression of tumor growth by the novel IGF1R kinase inhibitor A-928605

BACKGROUND: The insulin-like growth factor (IGF) axis is an important signaling pathway in the growth and survival of many cell and tissue types. This pathway has also been implicated in many aspects of cancer progression from tumorigenesis to metastasis. The multiple roles of IGF signaling in cance...

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Detalles Bibliográficos
Autores principales: Pappano, William N, Jung, Paul M, Meulbroek, Jonathan A, Wang, Yi-Chun, Hubbard, Robert D, Zhang, Qian, Grudzien, Meagan M, Soni, Niru B, Johnson, Eric F, Sheppard, George S, Donawho, Cherrie, Buchanan, Fritz G, Davidsen, Steven K, Bell, Randy L, Wang, Jieyi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749869/
https://www.ncbi.nlm.nih.gov/pubmed/19732452
http://dx.doi.org/10.1186/1471-2407-9-314

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