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Presence of HER4 associates with increased sensitivity to Herceptin™ in patients with metastatic breast cancer
INTRODUCTION: HER2 overexpression, or rather HER2 gene amplification, is indicative for Herceptin therapy in both metastatic and pre-metastatic breast cancer patients. Patient's individual sensitivity to Herceptin treatment, however, varies enormously and spans from effectual responsiveness ove...
Autores principales: | Sassen, Andrea, Diermeier-Daucher, Simone, Sieben, Manuela, Ortmann, Olaf, Hofstaedter, Ferdinand, Schwarz, Stephan, Brockhoff, Gero |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750111/ https://www.ncbi.nlm.nih.gov/pubmed/19624808 http://dx.doi.org/10.1186/bcr2339 |
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