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Construction of an MUC-1 promoter driven, conditionally replicating adenovirus that expresses the sodium iodide symporter for gene therapy of breast cancer

INTRODUCTION: The sodium iodide symporter (NIS) directs the uptake and concentration of iodide in thyroid cells. This in turn allows radioiodine imaging and therapy for thyroid cancer. To extend the use of NIS-mediated radioiodine therapy to other types of cancer, we successfully transferred and exp...

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Detalles Bibliográficos
Autores principales: Trujillo, Miguel A, Oneal, Michael J, Davydova, Julia, Bergert, Elizabeth, Yamamoto, Masato, Morris, John C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750114/
https://www.ncbi.nlm.nih.gov/pubmed/19635153
http://dx.doi.org/10.1186/bcr2342