Pharmacokinetics of epinephrine in patients with septic shock: modelization and interaction with endogenous neurohormonal status

INTRODUCTION: In septic patients, an unpredictable response to epinephrine may be due to pharmacodynamic factors or to non-linear pharmacokinetics. The purpose of this study was to investigate the pharmacokinetics of epinephrine and its determinants in patients with septic shock. METHODS: Thirty-eig...

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Detalles Bibliográficos
Autores principales: Abboud, Imad, Lerolle, Nicolas, Urien, Saik, Tadié, Jean-Marc, Leviel, Françoise, Fagon, Jean-Yves, Faisy, Christophe
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750169/
https://www.ncbi.nlm.nih.gov/pubmed/19622169
http://dx.doi.org/10.1186/cc7972

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