Cargando…

Enhanced Hypothalamic Glucose Sensing in Obesity: Alteration of Redox Signaling

OBJECTIVE: Recent data demonstrated that glucose sensing in different tissues is initiated by an intracellular redox signaling pathway in physiological conditions. However, the relevance of such a mechanism in metabolic disease is not known. The aim of the present study was to determine whether brai...

Descripción completa

Detalles Bibliográficos
Autores principales:	Colombani, Anne-Laure, Carneiro, Lionel, Benani, Alexandre, Galinier, Anne, Jaillard, Tristan, Duparc, Thibaut, Offer, Géraldine, Lorsignol, Anne, Magnan, Christophe, Casteilla, Louis, Pénicaud, Luc, Leloup, Corinne
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2009
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750216/ https://www.ncbi.nlm.nih.gov/pubmed/19581415 http://dx.doi.org/10.2337/db09-0110

Ejemplares similares

Hypothalamic Reactive Oxygen Species Are Required for Insulin-Induced Food Intake Inhibition: An NADPH Oxidase–Dependent Mechanism
por: Jaillard, Tristan, et al.
Publicado: (2009)

Mitochondrial Reactive Oxygen Species Are Obligatory Signals for Glucose-Induced Insulin Secretion
por: Leloup, Corinne, et al.
Publicado: (2009)

Tissue Regeneration: The Dark Side of Opioids
por: Berthézène, Cécile Dromard, et al.
Publicado: (2021)

Mitochondrial Dynamin-Related Protein 1 (DRP1) translocation in response to cerebral glucose is impaired in a rat model of early alteration in hypothalamic glucose sensing
por: Desmoulins, Lucie, et al.
Publicado: (2018)

Pain sensing neurons promote tissue regeneration in adult mice
por: Rabiller, Lise, et al.
Publicado: (2021)

Recent Advances in the Cellular and Molecular Mechanisms of Hypothalamic Neuronal Glucose Detection
por: Fioramonti, Xavier, et al.
Publicado: (2017)

3D analysis of the whole subcutaneous adipose tissue reveals a complex spatial network of interconnected lobules with heterogeneous browning ability
por: Dichamp, Jules, et al.
Publicado: (2019)

Hypothalamic sensing of ketone bodies after prolonged cerebral exposure leads to metabolic control dysregulation
por: Carneiro, Lionel, et al.
Publicado: (2016)

Hypothalamic S-Nitrosylation Contributes to the Counter-Regulatory Response Impairment following Recurrent Hypoglycemia
por: Fioramonti, Xavier, et al.
Publicado: (2013)

Fatty Acid Transporter CD36 Mediates Hypothalamic Effect of Fatty Acids on Food Intake in Rats
por: Moullé, Valentine S., et al.
Publicado: (2013)

Lactate Fluxes and Plasticity of Adipose Tissues: A Redox Perspective
por: Lagarde, Damien, et al.
Publicado: (2021)

Opioids prevent regeneration in adult mammals through inhibition of ROS production
por: Labit, Elodie, et al.
Publicado: (2018)

The histone acetyltransferase MOF activates hypothalamic polysialylation to prevent diet-induced obesity in mice
por: Brenachot, Xavier, et al.
Publicado: (2014)

Lactate fluxes mediated by the monocarboxylate transporter-1 are key determinants of the metabolic activity of beige adipocytes
por: Lagarde, Damien, et al.
Publicado: (2020)

Anti-Obesity Sodium Tungstate Treatment Triggers Axonal and Glial Plasticity in Hypothalamic Feeding Centers
por: Amigó-Correig, Marta, et al.
Publicado: (2012)

From whole-organ imaging to in-silico blood flow modeling: A new multi-scale network analysis for revisiting tissue functional anatomy
por: Kennel, Pol, et al.
Publicado: (2020)

A Physiological Increase of Insulin in the Olfactory Bulb Decreases Detection of a Learned Aversive Odor and Abolishes Food Odor-Induced Sniffing Behavior in Rats
por: Aimé, Pascaline, et al.
Publicado: (2012)

Explainable machine learning framework to predict personalized physiological aging
por: Bernard, David, et al.
Publicado: (2023)

Mens sana in corpore sano: Does the Glycemic Index Have a Role to Play?
por: Carneiro, Lionel, et al.
Publicado: (2020)

Brain Glucagon-Like Peptide-1 Regulates Arterial Blood Flow, Heart Rate, and Insulin Sensitivity
por: Cabou, Cendrine, et al.
Publicado: (2008)

Driving regeneration, instead of healing, in adult mammals: the decisive role of resident macrophages through efferocytosis
por: Rabiller, Lise, et al.
Publicado: (2021)

Plasticity of the Melanocortin System: Determinants and Possible Consequences on Food Intake
por: Nuzzaci, Danaé, et al.
Publicado: (2015)

Hypothalamus-Olfactory System Crosstalk: Orexin A Immunostaining in Mice
por: Gascuel, Jean, et al.
Publicado: (2012)

Ventromedial Hypothalamic Nitric Oxide Production Is Necessary for Hypoglycemia Detection and Counterregulation
por: Fioramonti, Xavier, et al.
Publicado: (2010)

Defective autophagy in Sf1 neurons perturbs the metabolic response to fasting and causes mitochondrial dysfunction
por: Coupé, Bérengère, et al.
Publicado: (2021)

Prandial States Modify the Reactivity of the Gustatory Cortex Using Gustatory Evoked Potentials in Humans
por: Jacquin-Piques, Agnès, et al.
Publicado: (2016)

Taste of Fat and Obesity: Different Hypotheses and Our Point of View
por: Brondel, Laurent, et al.
Publicado: (2022)

A New Role for Browning as a Redox and Stress Adaptive Mechanism?
por: Jeanson, Yannick, et al.
Publicado: (2015)

Loss of functional OPA1 unbalances redox state: implications in dominant optic atrophy pathogenesis
por: Millet, Aurélie M. C., et al.
Publicado: (2016)

Diabetic β-Cells Can Achieve Self-Protection against Oxidative Stress through an Adaptive Up-Regulation of Their Antioxidant Defenses
por: Lacraz, Grégory, et al.
Publicado: (2009)

Differential Cerebral Gustatory Responses to Sucrose, Aspartame, and Stevia Using Gustatory Evoked Potentials in Humans
por: Mouillot, Thomas, et al.
Publicado: (2020)

AMPK activation caused by reduced liver lactate metabolism protects against hepatic steatosis in MCT1 haploinsufficient mice
por: Carneiro, Lionel, et al.
Publicado: (2017)

High-Sugar Diet Disrupts Hypothalamic but Not Cerebral Cortex Redox Homeostasis
por: Żebrowska, Ewa, et al.
Publicado: (2020)

Cerebral Cell Renewal in Adult Mice Controls the Onset of Obesity
por: Gouazé, Alexandra, et al.
Publicado: (2013)

Brain Control of Plasma Cholesterol Involves Polysialic Acid Molecules in the Hypothalamus
por: Brenachot, Xavier, et al.
Publicado: (2017)

Hypothalamic lipoma and growth hormone deficiency
por: Rochtus, Anne, et al.
Publicado: (2020)

Modulation of large dense core vesicle insulin content mediates rhythmic hormone release from pancreatic beta cells over the 24h cycle
por: Quinault, Aurore, et al.
Publicado: (2018)

Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy
por: Seifinejad, Ali, et al.
Publicado: (2023)

Identification of Hypothalamic Glucoregulatory Neurons That Sense and Respond to Changes in Glycemia
por: Deem, Jennifer D., et al.
Publicado: (2023)

COVID-19, sens chimiques et pathologies métaboliques
por: Pénicaud, Luc
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_174a04nmcohisocgk04rp4aaqj