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Immune Depletion With Cellular Mobilization Imparts Immunoregulation and Reverses Autoimmune Diabetes in Nonobese Diabetic Mice
OBJECTIVE: The autoimmune destruction of β-cells in type 1 diabetes results in a loss of insulin production and glucose homeostasis. As such, an immense interest exists for the development of therapies capable of attenuating this destructive process through restoration of proper immune recognition....
Autores principales: | Parker, Matthew J., Xue, Song, Alexander, John J., Wasserfall, Clive H., Campbell-Thompson, Martha L., Battaglia, Manuela, Gregori, Silvia, Mathews, Clayton E., Song, Sihong, Troutt, Misty, Eisenbeis, Scott, Williams, John, Schatz, Desmond A., Haller, Michael J., Atkinson, Mark A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750219/ https://www.ncbi.nlm.nih.gov/pubmed/19628781 http://dx.doi.org/10.2337/db09-0557 |
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