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TIMP3 Is Reduced in Atherosclerotic Plaques From Subjects With Type 2 Diabetes and Increased by SirT1
OBJECTIVE: Atherosclerosis is accelerated in subjects with type 2 diabetes by unknown mechanisms. We identified tissue inhibitor of metalloproteinase 3 (TIMP3), the endogenous inhibitor of A disintegrin and metalloprotease domain 17 (ADAM17) and other matrix metalloproteinases (MMPs), as a gene modi...
Autores principales: | Cardellini, Marina, Menghini, Rossella, Martelli, Eugenio, Casagrande, Viviana, Marino, Arianna, Rizza, Stefano, Porzio, Ottavia, Mauriello, Alessandro, Solini, Anna, Ippoliti, Arnaldo, Lauro, Renato, Folli, Franco, Federici, Massimo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750223/ https://www.ncbi.nlm.nih.gov/pubmed/19581416 http://dx.doi.org/10.2337/db09-0280 |
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