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Dyslipidemia-Induced Neuropathy in Mice: The Role of oxLDL/LOX-1

OBJECTIVE: Neuropathy is a frequent and severe complication of diabetes. Multiple metabolic defects in type 2 diabetic patients result in oxidative injury of dorsal root ganglia (DRG) neurons. Our previous work focused on hyperglycemia clearly demonstrates induction of mitochondrial oxidative stress...

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Detalles Bibliográficos
Autores principales: Vincent, Andrea M., Hayes, John M., McLean, Lisa L., Vivekanandan-Giri, Anuradha, Pennathur, Subramaniam, Feldman, Eva L.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750230/
https://www.ncbi.nlm.nih.gov/pubmed/19592619
http://dx.doi.org/10.2337/db09-0047