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Rac1 Is Required for Cardiomyocyte Apoptosis During Hyperglycemia

OBJECTIVE: Hyperglycemia induces reactive oxygen species (ROS) and apoptosis in cardiomyocytes, which contributes to diabetic cardiomyopathy. The present study was to investigate the role of Rac1 in ROS production and cardiomyocyte apoptosis during hyperglycemia. RESEARCH DESIGN AND METHODS: Mice wi...

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Detalles Bibliográficos
Autores principales:	Shen, E., Li, Yanwen, Li, Ying, Shan, Limei, Zhu, Huaqing, Feng, Qingping, Arnold, J. Malcolm O., Peng, Tianqing
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2009
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750234/ https://www.ncbi.nlm.nih.gov/pubmed/19592621 http://dx.doi.org/10.2337/db08-0617

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