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Two adjacent nuclear factor-binding domains activate expression from the human PRNP promoter
BACKGROUND: The transmissible spongiform encephalopathies (TSEs) comprise a group of fatal degenerative neurological diseases in humans and other mammals. After infection, the cellular prion protein isoform PrP(C )is converted to the pathological PrP(SC )scrapie isoform. The continued conversion of...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751769/ https://www.ncbi.nlm.nih.gov/pubmed/19740434 http://dx.doi.org/10.1186/1756-0500-2-178 |