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Two adjacent nuclear factor-binding domains activate expression from the human PRNP promoter

BACKGROUND: The transmissible spongiform encephalopathies (TSEs) comprise a group of fatal degenerative neurological diseases in humans and other mammals. After infection, the cellular prion protein isoform PrP(C )is converted to the pathological PrP(SC )scrapie isoform. The continued conversion of...

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Detalles Bibliográficos
Autores principales:	Taheny, Michael J, Izkhakov, Nerik, Vostrov, Alexander A, Quitschke, Wolfgang W
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751769/ https://www.ncbi.nlm.nih.gov/pubmed/19740434 http://dx.doi.org/10.1186/1756-0500-2-178

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