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Sequence features associated with microRNA strand selection in humans and flies
BACKGROUND: During microRNA (miRNA) maturation in humans and flies, Drosha and Dicer cut the precursor transcript, thereby producing a short RNA duplex. One strand of this duplex becomes a functional component of the RNA-Induced Silencing Complex (RISC), while the other is eliminated. While thermody...
Autores principales: | Hu, Hai Yang, Yan, Zheng, Xu, Ying, Hu, Hao, Menzel, Corinna, Zhou, Yan Hong, Chen, Wei, Khaitovich, Philipp |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751786/ https://www.ncbi.nlm.nih.gov/pubmed/19732433 http://dx.doi.org/10.1186/1471-2164-10-413 |
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