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Functional, Non-Clonal IgM(a)-Restricted B Cell Receptor Interactions with the HIV-1 Envelope gp41 Membrane Proximal External Region

The membrane proximal external region (MPER) of HIV-1 gp41 has several features that make it an attractive antibody-based vaccine target, but eliciting an effective gp41 MPER-specific protective antibody response remains elusive. One fundamental issue is whether the failure to make gp41 MPER-specifi...

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Detalles Bibliográficos
Autores principales: Verkoczy, Laurent, Moody, M. Anthony, Holl, T. Matt, Bouton-Verville, Hilary, Scearce, Richard M., Hutchinson, Jennifer, Alam, S. Munir, Kelsoe, Garnett, Haynes, Barton F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751816/
https://www.ncbi.nlm.nih.gov/pubmed/19806186
http://dx.doi.org/10.1371/journal.pone.0007215