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Determining Protein Complex Connectivity Using a Probabilistic Deletion Network Derived from Quantitative Proteomics
Protein complexes are key molecular machines executing a variety of essential cellular processes. Despite the availability of genome-wide protein-protein interaction studies, determining the connectivity between proteins within a complex remains a major challenge. Here we demonstrate a method that i...
Autores principales: | Sardiu, Mihaela E., Gilmore, Joshua M., Carrozza, Michael J., Li, Bing, Workman, Jerry L., Florens, Laurence, Washburn, Michael P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751824/ https://www.ncbi.nlm.nih.gov/pubmed/19806189 http://dx.doi.org/10.1371/journal.pone.0007310 |
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