KSHV Manipulates Notch Signaling by DLL4 and JAG1 to Alter Cell Cycle Genes in Lymphatic Endothelia

Increased expression of Notch signaling pathway components is observed in Kaposi sarcoma (KS) but the mechanism underlying the manipulation of the canonical Notch pathway by the causative agent of KS, Kaposi sarcoma herpesvirus (KSHV), has not been fully elucidated. Here, we describe the mechanism t...

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Detalles Bibliográficos
Autores principales: Emuss, Victoria, Lagos, Dimitrios, Pizzey, Arnold, Gratrix, Fiona, Henderson, Stephen R., Boshoff, Chris
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751827/
https://www.ncbi.nlm.nih.gov/pubmed/19816565
http://dx.doi.org/10.1371/journal.ppat.1000616

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