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Emerging common themes in regulation of PIKKs and PI3Ks
Phosphatidylinositol-3 kinase-related kinases (PIKKs) comprise a family of protein kinases that respond to various stresses, including DNA damage, blocks in DNA replication, availability of nutrients and errors in mRNA splicing. PIKKs are characterized by the presence of a conserved kinase domain (K...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752028/ https://www.ncbi.nlm.nih.gov/pubmed/19779456 http://dx.doi.org/10.1038/emboj.2009.281 |