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Emerging common themes in regulation of PIKKs and PI3Ks

Phosphatidylinositol-3 kinase-related kinases (PIKKs) comprise a family of protein kinases that respond to various stresses, including DNA damage, blocks in DNA replication, availability of nutrients and errors in mRNA splicing. PIKKs are characterized by the presence of a conserved kinase domain (K...

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Detalles Bibliográficos
Autores principales:	Lempiäinen, Harri, Halazonetis, Thanos D
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2009
Materias:	EMBO Member's Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752028/ https://www.ncbi.nlm.nih.gov/pubmed/19779456 http://dx.doi.org/10.1038/emboj.2009.281

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