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Activin/Nodal Inhibition Alone Accelerates Highly Efficient Neural Conversion from Human Embryonic Stem Cells and Imposes a Caudal Positional Identity

BACKGROUND: Neural conversion from human embryonic stem cells (hESCs) has been demonstrated in a variety of systems including chemically defined suspension culture, not requiring extrinsic signals, as well as in an adherent culture method that involves dual SMAD inhibition using Noggin and SB431542...

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Detalles Bibliográficos
Autores principales:	Patani, Rickie, Compston, Alastair, Puddifoot, Clare A., Wyllie, David J. A., Hardingham, Giles E., Allen, Nicholas D., Chandran, Siddharthan
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752165/ https://www.ncbi.nlm.nih.gov/pubmed/19806200 http://dx.doi.org/10.1371/journal.pone.0007327

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