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The role of cooperativity with Src in oncogenic transformation mediated by non-small cell lung cancer-associated EGF receptor mutants
Non-small cell lung cancer (NSCLC)-associated epidermal growth factor receptor (EGFR) mutants are constitutively active and induce ligand-independent transformation in nonmalignant cell lines. We investigated the possibility that the ability of mutant EGFRs to transform cells reflects a constitutive...
Autores principales: | Chung, Byung Min, Dimri, Manjari, George, Manju, Reddi, Alagarsamy Lakku, Chen, Gengsheng, Band, Vimla, Band, Hamid |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752420/ https://www.ncbi.nlm.nih.gov/pubmed/19305428 http://dx.doi.org/10.1038/onc.2009.31 |
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