Cargando…
Copy number variation and association analysis of SHANK3 as a candidate gene for autism in the IMGSAC collection
SHANK3 is located on chromosome 22q13.3 and encodes a scaffold protein that is found in excitatory synapses opposite the pre-synaptic active zone. SHANK3 is a binding partner of neuroligins, some of whose genes contain mutations in a small subset of individuals with autism. In individuals with autis...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752466/ https://www.ncbi.nlm.nih.gov/pubmed/19384346 http://dx.doi.org/10.1038/ejhg.2009.47 |