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PhyloDet: a scalable visualization tool for mapping multiple traits to large evolutionary trees

Summary: Evolutionary biologists are often interested in finding correlations among biological traits across a number of species, as such correlations may lead to testable hypotheses about the underlying function. Because some species are more closely related than others, computing and visualizing t...

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Detalles Bibliográficos
Autores principales: Lee, Bongshin, Nachmanson, Lev, Robertson, George, Carlson, Jonathan M., Heckerman, David
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752614/
https://www.ncbi.nlm.nih.gov/pubmed/19633096
http://dx.doi.org/10.1093/bioinformatics/btp454
Descripción
Sumario:Summary: Evolutionary biologists are often interested in finding correlations among biological traits across a number of species, as such correlations may lead to testable hypotheses about the underlying function. Because some species are more closely related than others, computing and visualizing these correlations must be done in the context of the evolutionary tree that relates species. In this note, we introduce PhyloDet (short for PhyloDetective), an evolutionary tree visualization tool that enables biologists to visualize multiple traits mapped to the tree. Availability: http://research.microsoft.com/cue/phylodet/ Contact: bongshin@microsoft.com.