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Genoscape: a Cytoscape plug-in to automate the retrieval and integration of gene expression data and molecular networks

Summary: Genoscape is an open-source Cytoscape plug-in that visually integrates gene expression data sets from GenoScript, a transcriptomic database, and KEGG pathways into Cytoscape networks. The generated visualisation highlights gene expression changes and their statistical significance. The plug...

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Detalles Bibliográficos
Autores principales: Clément-Ziza, Mathieu, Malabat, Christophe, Weber, Christian, Moszer, Ivan, Aittokallio, Tero, Letondal, Catherine, Rousseau, Sandrine
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752617/
https://www.ncbi.nlm.nih.gov/pubmed/19654116
http://dx.doi.org/10.1093/bioinformatics/btp464
Descripción
Sumario:Summary: Genoscape is an open-source Cytoscape plug-in that visually integrates gene expression data sets from GenoScript, a transcriptomic database, and KEGG pathways into Cytoscape networks. The generated visualisation highlights gene expression changes and their statistical significance. The plug-in also allows one to browse GenoScript or import transcriptomic data from other sources through tab-separated text files. Genoscape has been successfully used by researchers to investigate the results of gene expression profiling experiments. Availability: Genoscape is an open-source software freely available from the Genoscape webpage (http://www.pasteur.fr/recherche/unites/Gim/genoscape/). Installation instructions and tutorial can also be found at this URL. Contact: Mathieu.clement-ziza@biotec.tu-dresden.de; sandrine.rousseau@pasteur.fr Supplementary information: Supplementary data are available at Bioinformatics online.