Antibiotic-induced Severe Neutropenia with Multidrug-Dependent Antineutrophil Antibodies Developed in A Child with Streptococcus pneumoniae Infection

Drug-induced neutropenia (DIN), particularly that in which antibiotic-dependent antineutrophil antibodies have been detected, is a rare disorder. We report the case of a child with pneumococcal pneumonia, who experienced severe neutropenia during various antibiotic treatments. We detected 4 kinds (c...

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Detalles Bibliográficos
Autores principales: Lee, Young-Ho, Lee, Ha-Baik, Kim, Jung-Yun, Lim, Yeon-Jung, Shin, Su-A, Han, Tae-Hee
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2009
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752789/
https://www.ncbi.nlm.nih.gov/pubmed/19795004
http://dx.doi.org/10.3346/jkms.2009.24.5.975
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author Lee, Young-Ho
Lee, Ha-Baik
Kim, Jung-Yun
Lim, Yeon-Jung
Shin, Su-A
Han, Tae-Hee
author_facet Lee, Young-Ho
Lee, Ha-Baik
Kim, Jung-Yun
Lim, Yeon-Jung
Shin, Su-A
Han, Tae-Hee
author_sort Lee, Young-Ho
collection PubMed
description Drug-induced neutropenia (DIN), particularly that in which antibiotic-dependent antineutrophil antibodies have been detected, is a rare disorder. We report the case of a child with pneumococcal pneumonia, who experienced severe neutropenia during various antibiotic treatments. We detected 4 kinds (cefotaxim, augmentin, vancomycin, and tobramycin) of antibiotic-dependent antineutrophil antibodies by using the mixed passive hemagglutination assay (MPHA) technique with this child.
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spelling pubmed-27527892009-10-01 Antibiotic-induced Severe Neutropenia with Multidrug-Dependent Antineutrophil Antibodies Developed in A Child with Streptococcus pneumoniae Infection Lee, Young-Ho Lee, Ha-Baik Kim, Jung-Yun Lim, Yeon-Jung Shin, Su-A Han, Tae-Hee J Korean Med Sci Case Report Drug-induced neutropenia (DIN), particularly that in which antibiotic-dependent antineutrophil antibodies have been detected, is a rare disorder. We report the case of a child with pneumococcal pneumonia, who experienced severe neutropenia during various antibiotic treatments. We detected 4 kinds (cefotaxim, augmentin, vancomycin, and tobramycin) of antibiotic-dependent antineutrophil antibodies by using the mixed passive hemagglutination assay (MPHA) technique with this child. The Korean Academy of Medical Sciences 2009-10 2009-09-23 /pmc/articles/PMC2752789/ /pubmed/19795004 http://dx.doi.org/10.3346/jkms.2009.24.5.975 Text en Copyright © 2009 The Korean Academy of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lee, Young-Ho
Lee, Ha-Baik
Kim, Jung-Yun
Lim, Yeon-Jung
Shin, Su-A
Han, Tae-Hee
Antibiotic-induced Severe Neutropenia with Multidrug-Dependent Antineutrophil Antibodies Developed in A Child with Streptococcus pneumoniae Infection
title Antibiotic-induced Severe Neutropenia with Multidrug-Dependent Antineutrophil Antibodies Developed in A Child with Streptococcus pneumoniae Infection
title_full Antibiotic-induced Severe Neutropenia with Multidrug-Dependent Antineutrophil Antibodies Developed in A Child with Streptococcus pneumoniae Infection
title_fullStr Antibiotic-induced Severe Neutropenia with Multidrug-Dependent Antineutrophil Antibodies Developed in A Child with Streptococcus pneumoniae Infection
title_full_unstemmed Antibiotic-induced Severe Neutropenia with Multidrug-Dependent Antineutrophil Antibodies Developed in A Child with Streptococcus pneumoniae Infection
title_short Antibiotic-induced Severe Neutropenia with Multidrug-Dependent Antineutrophil Antibodies Developed in A Child with Streptococcus pneumoniae Infection
title_sort antibiotic-induced severe neutropenia with multidrug-dependent antineutrophil antibodies developed in a child with streptococcus pneumoniae infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752789/
https://www.ncbi.nlm.nih.gov/pubmed/19795004
http://dx.doi.org/10.3346/jkms.2009.24.5.975
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