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Sequential Use of Transcriptional Profiling, Expression Quantitative Trait Mapping, and Gene Association Implicates MMP20 in Human Kidney Aging

Kidneys age at different rates, such that some people show little or no effects of aging whereas others show rapid functional decline. We sequentially used transcriptional profiling and expression quantitative trait loci (eQTL) mapping to narrow down which genes to test for association with kidney a...

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Detalles Bibliográficos
Autores principales:	Wheeler, Heather E., Metter, E. Jeffrey, Tanaka, Toshiko, Absher, Devin, Higgins, John, Zahn, Jacob M., Wilhelmy, Julie, Davis, Ronald W., Singleton, Andrew, Myers, Richard M., Ferrucci, Luigi, Kim, Stuart K.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752811/ https://www.ncbi.nlm.nih.gov/pubmed/19834535 http://dx.doi.org/10.1371/journal.pgen.1000685

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