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Tropomodulin1 is required for membrane skeleton organization and hexagonal geometry of fiber cells in the mouse lens
Hexagonal packing geometry is a hallmark of close-packed epithelial cells in metazoans. Here, we used fiber cells of the vertebrate eye lens as a model system to determine how the membrane skeleton controls hexagonal packing of post-mitotic cells. The membrane skeleton consists of spectrin tetramers...
Autores principales: | Nowak, Roberta B., Fischer, Robert S., Zoltoski, Rebecca K., Kuszak, Jerome R., Fowler, Velia M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753162/ https://www.ncbi.nlm.nih.gov/pubmed/19752024 http://dx.doi.org/10.1083/jcb.200905065 |
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