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Phosphodiesterase-5 inhibitors have distinct effects on the hemodynamics of the liver
BACKGROUND: The NO - cGMP system plays a key role in the regulation of sinusoidal tonus and liver blood flow with phosphodiesterase-5 (PDE-5) terminating the dilatory action of cGMP. We, therefore, investigated the effects of PDE-5 inhibitors on hepatic and systemic hemodynamics in rats. METHODS: He...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753560/ https://www.ncbi.nlm.nih.gov/pubmed/19765284 http://dx.doi.org/10.1186/1471-230X-9-69 |