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Beta4 integrin promotes osteosarcoma metastasis and interacts with ezrin

The development of pulmonary metastasis is the major cause of death in osteosarcoma, and its molecular basis is poorly understood. In this study, we show that β4 integrin is highly expressed in human osteosarcoma cell lines and tumor samples. Furthermore, highly metastatic MNNG-HOS cells have increa...

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Detalles Bibliográficos
Autores principales:	Wan, Xiaolin, Kim, Su Young, Guenther, Lillian M, Mendoza, Arnulfo, Briggs, Joseph, Yeung, Choh, Currier, Duane, Zhang, Hua, Mackall, Crystal, Li, Wan-Ju, Tuan, Rocky S, Deyrup, Andrea T, Khanna, Chand, Helman, Lee
Formato:	Texto
Lenguaje:	English
Publicado:	2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753583/ https://www.ncbi.nlm.nih.gov/pubmed/19597468 http://dx.doi.org/10.1038/onc.2009.206

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