Involvement of insulin-degrading enzyme in the clearance of beta-amyloid at the blood-CSF barrier: Consequences of lead exposure

BACKGROUND: Alzheimer's disease (AD) is characterized by the deposition of beta-amyloid (Aβ) peptides in the brain extracellular matrix, resulting in pathological changes and neurobehavioral deficits. Previous work from this laboratory demonstrated that the choroid plexus (CP) possesses the cap...

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Detalles Bibliográficos
Autores principales: Behl, Mamta, Zhang, Yanshu, Zheng, Wei
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753621/
https://www.ncbi.nlm.nih.gov/pubmed/19747378
http://dx.doi.org/10.1186/1743-8454-6-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753621/
https://www.ncbi.nlm.nih.gov/pubmed/19747378
http://dx.doi.org/10.1186/1743-8454-6-11

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