Cargando…

Dimethylarginine Dimethylaminohydrolase-1 Transgenic Mice Are Not Protected from Ischemic Stroke

BACKGROUND: Methylated arginines are endogenous analogues of L-arginine, the substrate for nitric oxide (NO) synthase. Asymmetric dimethylarginine (ADMA) interferes with NO formation, causing endothelial dysfunction. ADMA is a predictor of cardiovascular events and mortality in humans. It is elimina...

Descripción completa

Detalles Bibliográficos
Autores principales:	Leypoldt, Frank, Choe, Chi-Un, Gelderblom, Mathias, von Leitner, Eike-Christin, Atzler, Dorothee, Schwedhelm, Edzard, Gerloff, Christian, Sydow, Karsten, Böger, Rainer H., Magnus, Tim
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753663/ https://www.ncbi.nlm.nih.gov/pubmed/19809508 http://dx.doi.org/10.1371/journal.pone.0007337

Ejemplares similares

Dimethylarginine Dimethylaminohydrolase1 Is an Organ-Specific Mediator of End Organ Damage in a Murine Model of Hypertension
por: Sydow, Karsten, et al.
Publicado: (2012)

A multicentric consortium study demonstrates that dimethylarginine dimethylaminohydrolase 2 is not a dimethylarginine dimethylaminohydrolase
por: Ragavan, Vinitha N., et al.
Publicado: (2023)

Associations of circulating dimethylarginines with the metabolic syndrome in the Framingham Offspring study
por: Yola, Ibrahim Musa, et al.
Publicado: (2021)

Incidence of All-Cause and Cardiovascular Mortality Predicted by Symmetric Dimethylarginine in the Population-Based Study of Health in Pomerania
por: Schwedhelm, Edzard, et al.
Publicado: (2014)

Population kinetics of homoarginine and optimized supplementation for cardiovascular risk reduction
por: Kleist, Christine J., et al.
Publicado: (2022)

Dimethylarginine dimethylaminohydrolase I enhances tumour growth and angiogenesis
por: Kostourou, V, et al.
Publicado: (2002)

Dimethylarginine dimethylaminohydrolase 1 is involved in spinal nociceptive plasticity
por: D'Mello, Richard, et al.
Publicado: (2015)

Dimethylarginine dimethylaminohydrolase 2 promotes tumor angiogenesis in lung adenocarcinoma
por: Shiozawa, Toshihiro, et al.
Publicado: (2015)

Divergent Dimethylarginine Dimethylaminohydrolase Isoenzyme Expression in the Central Nervous System
por: Kozlova, Alena A., et al.
Publicado: (2021)

Homoarginine- and Creatine-Dependent Gene Regulation in Murine Brains with l-Arginine:Glycine Amidinotransferase Deficiency
por: Jensen, Märit, et al.
Publicado: (2020)

Ligand-Dependent Dynamics of the Active-Site Lid in Bacterial Dimethylarginine Dimethylaminohydrolase
por: Rasheed, Masooma, et al.
Publicado: (2014)

Inhibitors of the Hydrolytic Enzyme Dimethylarginine Dimethylaminohydrolase (DDAH): Discovery, Synthesis and Development
por: Murphy, Rhys B., et al.
Publicado: (2016)

Regulation of dimethylarginine dimethylaminohydrolase 2 expression by NF-κB acetylation
por: Li, Jiaqi, et al.
Publicado: (2021)

Association of Asymmetric and Symmetric Dimethylarginine with Inflammation in the Population-Based Study of Health in Pomerania
por: Winkler, Martin Sebastian, et al.
Publicado: (2023)

Association of Asymmetric Dimethylarginine and Diastolic Dysfunction in Patients with Hypertrophic Cardiomyopathy
por: Cordts, Kathrin, et al.
Publicado: (2019)

Diurnal Variation of L-Arginine and the Cardiovascular Risk Markers Asymmetric and Symmetric Dimethylarginine and Homoarginine in Rotating Night Shift Workers and Controls
por: Hannemann, Juliane, et al.
Publicado: (2023)

Mechanical force promotes dimethylarginine dimethylaminohydrolase 1-mediated hydrolysis of the metabolite asymmetric dimethylarginine to enhance bone formation
por: Xie, Ziang, et al.
Publicado: (2022)

A Functional Variant of the Dimethylarginine Dimethylaminohydrolase-2 Gene Is Associated with Insulin Sensitivity
por: Andreozzi, Francesco, et al.
Publicado: (2012)

Dimethylarginine dimethylaminohydrolase-2 deficiency promotes vascular regeneration and attenuates pathological angiogenesis
por: Lange, Clemens, et al.
Publicado: (2016)

A study of endothelial function and circulating asymmetric dimethylarginine levels in people with Type 1 diabetes without macrovascular disease or microalbuminuria
por: Sibal, Latika, et al.
Publicado: (2009)

Overexpression of Dimethylarginine Dimethylaminohydrolase 1 Attenuates Airway Inflammation in a Mouse Model of Asthma
por: Kinker, Kayla G., et al.
Publicado: (2014)

Human dimethylarginine dimethylaminohydrolase 1 inhibition by proton pump inhibitors and the cardiovascular risk marker asymmetric dimethylarginine: in vitro and in vivo significance
por: Tommasi, S., et al.
Publicado: (2017)

Exploring the role of dimethylarginine dimethylaminohydrolase-mediated reduction in tissue asymmetrical dimethylarginine levels in cardio-protective mechanism of ischaemic postconditioning in rats
por: Kaur, Kamaldeep, et al.
Publicado: (2019)

Symmetrical (SDMA) and asymmetrical dimethylarginine (ADMA) in sepsis: high plasma levels as combined risk markers for sepsis survival
por: Winkler, Martin Sebastian, et al.
Publicado: (2018)

Cerebral Changes Occurring in Arginase and Dimethylarginine Dimethylaminohydrolase (DDAH) in a Rat Model of Sleeping Sickness
por: Amrouni, Donia, et al.
Publicado: (2011)

The association of dimethylarginine dimethylaminohydrolase 1 gene polymorphism with type 2 diabetes: a cohort study
por: Lu, Tse-Min, et al.
Publicado: (2011)

Asymmetric Dimethylarginine at Sea Level Is a Predictive Marker of Hypoxic Pulmonary Arterial Hypertension at High Altitude
por: Siques, Patricia, et al.
Publicado: (2019)

Homoarginine Associates with Carotid Intima-Media Thickness and Atrial Fibrillation and Predicts Adverse Events after Stroke
por: Schwieren, Laura, et al.
Publicado: (2023)

Low Homoarginine Levels in the Prognosis of Patients With Acute Chest Pain
por: Atzler, Dorothee, et al.
Publicado: (2016)

A new key player in VEGF-dependent angiogenesis in human hepatocellular carcinoma: dimethylarginine dimethylaminohydrolase 1
por: Buijs, Nikki, et al.
Publicado: (2017)

Inhibition of Dimethylarginine Dimethylaminohydrolase (DDAH) Enzymes as an Emerging Therapeutic Strategy to Target Angiogenesis and Vasculogenic Mimicry in Cancer
por: Hulin, Julie-Ann, et al.
Publicado: (2020)

Dissecting VEGF-induced acute versus chronic vascular hyperpermeability: Essential roles of dimethylarginine dimethylaminohydrolase-1
por: Wang, Ying, et al.
Publicado: (2021)

Correction: CD38 Exacerbates Focal Cytokine Production, Postischemic Inflammation and Brain Injury after Focal Cerebral Ischemia
por: Choe, Chi-un, et al.
Publicado: (2011)

CD38 Exacerbates Focal Cytokine Production, Postischemic Inflammation and Brain Injury after Focal Cerebral Ischemia
por: Choe, Chi-un, et al.
Publicado: (2011)

Biomarkers of the L-Arginine/Dimethylarginine/Nitric Oxide Pathway in People with Chronic Airflow Obstruction and Obstructive Sleep Apnoea
por: Hannemann, Juliane, et al.
Publicado: (2023)

L-Arginine and SDMA Serum Concentrations Are Associated with Subclinical Atherosclerosis in the Study of Health in Pomerania (SHIP)
por: Bahls, Martin, et al.
Publicado: (2015)

Dimethylarginine Dimethylaminohydrolase 2 (DDAH 2) Gene Polymorphism, Asymmetric Dimethylarginine (ADMA) Concentrations, and Risk of Coronary Artery Disease: A Case-Control Study
por: Xuan, Chao, et al.
Publicado: (2016)

Low-Circulating Homoarginine is Associated with Dilatation and Decreased Function of the Left Ventricle in the General Population
por: Bahls, Martin, et al.
Publicado: (2018)

A functional variant of the dimethylarginine dimethylaminohydrolase-2 gene is associated with myocardial infarction in type 2 diabetic patients
por: Mannino, Gaia Chiara, et al.
Publicado: (2019)

Dimethylarginine dimethylaminohydrolase in rat penile tissue: reduced enzyme activity is responsible for erectile dysfunction in a rat model of atherosclerosis
por: Park, K, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_4jjrnpncd9j4dg68mu2v14srt2