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Recombinant receptor-binding domain of SARS-CoV spike protein expressed in mammalian, insect and E. coli cells elicits potent neutralizing antibody and protective immunity

Severe acute respiratory syndrome (SARS) is a newly emerging infectious disease. The potential recurrence of the disease from animal reservoirs highlights the significance of development of safe and efficient vaccines to prevent a future SARS epidemic. In this study, we expressed the recombinant rec...

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Detalles Bibliográficos
Autores principales: Du, Lanying, Zhao, Guangyu, Chan, Chris C.S., Sun, Shihui, Chen, Min, Liu, Zhonghua, Guo, Hongxiang, He, Yuxian, Zhou, Yusen, Zheng, Bo-Jian, Jiang, Shibo
Formato: Texto
Lenguaje:English
Publicado: Elsevier Inc. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753736/
https://www.ncbi.nlm.nih.gov/pubmed/19683779
http://dx.doi.org/10.1016/j.virol.2009.07.018