Absolute Metabolite Concentrations and Implied Enzyme Active Site Occupancy in Escherichia coli

Absolute metabolite concentrations are critical to a quantitative understanding of cellular metabolism, as concentrations impact both the free energies and rates of metabolic reactions. Here we use liquid chromatography-tandem mass spectrometry to quantify more than 100 metabolite concentrations in...

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Detalles Bibliográficos
Autores principales: Bennett, Bryson D, Kimball, Elizabeth H, Gao, Melissa, Osterhout, Robin, Van Dien, Stephen J, Rabinowitz, Joshua D
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754216/
https://www.ncbi.nlm.nih.gov/pubmed/19561621
http://dx.doi.org/10.1038/nchembio.186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754216/
https://www.ncbi.nlm.nih.gov/pubmed/19561621
http://dx.doi.org/10.1038/nchembio.186

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