The formation of cysteine-linked dimers of BST-2/tetherin is important for inhibition of HIV-1 virus release but not for sensitivity to Vpu

BACKGROUND: The Human Immunodeficiency virus type 1 (HIV-1) Vpu protein enhances virus release from infected cells and induces proteasomal degradation of CD4. Recent work identified BST-2/CD317 as a host factor that inhibits HIV-1 virus release in a Vpu sensitive manner. A current working model prop...

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Detalles Bibliográficos
Autores principales: Andrew, Amy J, Miyagi, Eri, Kao, Sandra, Strebel, Klaus
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754425/
https://www.ncbi.nlm.nih.gov/pubmed/19737401
http://dx.doi.org/10.1186/1742-4690-6-80

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754425/
https://www.ncbi.nlm.nih.gov/pubmed/19737401
http://dx.doi.org/10.1186/1742-4690-6-80

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