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Fast optimization of statistical potentials for structurally constrained phylogenetic models
BACKGROUND: Statistical approaches for protein design are relevant in the field of molecular evolutionary studies. In recent years, new, so-called structurally constrained (SC) models of protein-coding sequence evolution have been proposed, which use statistical potentials to assess sequence-structu...
Autores principales: | Bonnard, Cécile, Kleinman, Claudia L, Rodrigue, Nicolas, Lartillot, Nicolas |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754480/ https://www.ncbi.nlm.nih.gov/pubmed/19740424 http://dx.doi.org/10.1186/1471-2148-9-227 |
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