Toll-Like Receptor 4 Decoy, TOY, Attenuates Gram-Negative Bacterial Sepsis

Lipopolysaccharide (LPS), the Gram-negative bacterial outer membrane glycolipid, induces sepsis through its interaction with myeloid differentiation protein-2 (MD-2) and Toll-like receptor 4 (TLR4). To block interaction between LPS/MD-2 complex and TLR4, we designed and generated soluble fusion prot...

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Detalles Bibliográficos
Autores principales: Jung, Keehoon, Lee, Jung-Eun, Kim, Hak-Zoo, Kim, Ho Min, Park, Beom Seok, Hwang, Seong-Ik, Lee, Jie-Oh, Kim, Sun Chang, Koh, Gou Young
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754608/
https://www.ncbi.nlm.nih.gov/pubmed/19816595
http://dx.doi.org/10.1371/journal.pone.0007403

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