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V3 Loop Sequence Space Analysis Suggests Different Evolutionary Patterns of CCR5- and CXCR4-Tropic HIV

The V3 loop of human immunodeficiency virus type 1 (HIV-1) is critical for coreceptor binding and is the main determinant of which of the cellular coreceptors, CCR5 or CXCR4, the virus uses for cell entry. The aim of this study is to provide a large-scale data driven analysis of HIV-1 coreceptor usa...

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Detalles Bibliográficos
Autores principales:	Bozek, Katarzyna, Thielen, Alexander, Sierra, Saleta, Kaiser, Rolf, Lengauer, Thomas
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754612/ https://www.ncbi.nlm.nih.gov/pubmed/19816596 http://dx.doi.org/10.1371/journal.pone.0007387

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