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Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation
XX female mammals undergo transcriptional silencing of most genes on one of their two X-chromosomes to equalize X-linked gene dosage with XY males in a process referred to as X-chromosome inactivation (XCI). XCI is a paradigm of epigenetic regulation1. Once enacted in individual cells of the early f...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754729/ https://www.ncbi.nlm.nih.gov/pubmed/19571810 http://dx.doi.org/10.1038/nature08161 |