Lead Optimization in Discovery Drug Metabolism and Pharmacokinetics/Case study: The Hepatitis C Virus (HCV) Protease Inhibitor SCH 503034

Lead optimization using drug metabolism and pharmacokinetics (DMPK) parameters has become one of the primary focuses of research organizations involved in drug discovery in the last decade. Using a combination of rapid in vivo and in vitro DMPK screening procedures on a large array of compounds duri...

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Detalles Bibliográficos
Autores principales: Cheng, K.-C., Korfmacher, Walter A., White, Ronald E., Njoroge, F. George
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2007
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754917/
https://www.ncbi.nlm.nih.gov/pubmed/19812732

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