Chemical Chaperone and Inhibitor Discovery: Potential Treatments for Protein Conformational Diseases

Protein misfolding and aggregation cause a large number of neurodegenerative diseases in humans due to (i) gain of function as observed in Alzheimer’s disease, Huntington’s disease, Parkinson’s disease, and Prion’s disease or (ii) loss of function as observed in cystic fibrosis and α1-antitrypsin de...

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Detalles Bibliográficos
Autores principales: Zhao, Jian-Hua, Liu, Hsuan-Liang, Lin, Hsin-Yi, Huang, Chih-Hung, Fang, Hsu-Wei, Chen, Shiao-Shing, Ho, Yih, Tsai, Wei-Bor, Chen, Wen-Yih
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2007
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754919/
https://www.ncbi.nlm.nih.gov/pubmed/19812735

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