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Both ischemic preconditioning and ghrelin administration protect hippocampus from ischemia/reperfusion and upregulate uncoupling protein-2

BACKGROUND: A major endogenous protective mechanism in many organs against ischemia/reperfusion (I/R) injury is ischemic preconditioning (IPC). By moderately uncoupling the mitochondrial respiratory chain and decreasing production of reactive oxygen species (ROS), IPC reduces apoptosis induced by I/...

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Detalles Bibliográficos
Autores principales: Liu, Yajun, Chen, Lianbi, Xu, Xiaoqun, Vicaut, Eric, Sercombe, Richard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754976/
https://www.ncbi.nlm.nih.gov/pubmed/19772611
http://dx.doi.org/10.1186/1472-6793-9-17