Critical role for ERK1/2 in bone marrow and fetal liver–derived primary megakaryocyte differentiation, motility, and proplatelet formation

OBJECTIVE: Megakaryopoiesis and platelet formation is a multistep process through which hematopoietic progenitor cells develop into mature megakaryocytes (MKs) and form proplatelets. The present study investigates the regulation of different steps of megakaryopoiesis (i.e., differentiation, migratio...

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Detalles Bibliográficos
Autores principales: Mazharian, Alexandra, Watson, Steve P., Séverin, Sonia
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science Inc 2009
Materias:
Megakaryocytopoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755112/
https://www.ncbi.nlm.nih.gov/pubmed/19619605
http://dx.doi.org/10.1016/j.exphem.2009.07.006

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