Cargando…

An RNA dependent RNA polymerase formed by hTERT and the RNase MRP RNA

Constitutive expression of telomerase in human cells prevents the onset of senescence and crisis by maintaining telomere homeostasis. However, accumulating evidence suggests that the human telomerase catalytic subunit (hTERT) contributes to cell physiology independent of its ability to elongate telo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maida, Yoshiko, Yasukawa, Mami, Furuuchi, Miho, Lassmann, Timo, Possemato, Richard, Okamoto, Naoko, Kasim, Vivi, Hayashizaki, Yoshihide, Hahn, William C., Masutomi, Kenkichi
Formato:	Texto
Lenguaje:	English
Publicado:	2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755635/ https://www.ncbi.nlm.nih.gov/pubmed/19701182 http://dx.doi.org/10.1038/nature08283

Ejemplares similares

Off-Target Effect of Endogenous siRNA Derived from RMRP in Human Cells
por: Maida, Yoshiko, et al.
Publicado: (2013)

Semi-quantitative Detection of RNA-dependent RNA Polymerase Activity of Human Telomerase Reverse Transcriptase Protein
por: Maida, Yoshiko, et al.
Publicado: (2018)

Telomerase Reverse Transcriptase Regulates microRNAs
por: Lassmann, Timo, et al.
Publicado: (2015)

CDK1 dependent phosphorylation of hTERT contributes to cancer progression
por: Yasukawa, Mami, et al.
Publicado: (2020)

Two-step cleavage of hairpin RNA with 5' overhangs by human DICER
por: Ando, Yoshinari, et al.
Publicado: (2011)

RNA‐dependent RNA polymerase, RdRP, a promising therapeutic target for cancer and potentially COVID‐19
por: Machitani, Mitsuhiro, et al.
Publicado: (2020)

Eribulin Mesylate Targets Human Telomerase Reverse Transcriptase in Ovarian Cancer Cells
por: Yamaguchi, Satoko, et al.
Publicado: (2014)

RNase MRP and the RNA processing cascade in the eukaryotic ancestor
por: Woodhams, Michael D, et al.
Publicado: (2007)

A Novel Long Non-Coding RNA in the hTERT Promoter Region Regulates hTERT Expression
por: Malhotra, Sanandan, et al.
Publicado: (2017)

Footprinting analysis of interactions between the largest eukaryotic RNase P/MRP protein Pop1 and RNase P/MRP RNA components
por: Fagerlund, Robert D., et al.
Publicado: (2015)

Viperin mRNA is a novel target for the human RNase MRP/RNase P endoribonuclease
por: Mattijssen, Sandy, et al.
Publicado: (2010)

Telomerase reverse transcriptase moonlights: Therapeutic targets beyond telomerase
por: Maida, Yoshiko, et al.
Publicado: (2015)

Dynamic localization of RNase MRP RNA in the nucleolus observed by fluorescent RNA cytochemistry in living cells
Publicado: (1995)

RNase MRP Cleaves Pre-tRNA(Ser-Met) in the tRNA Maturation Pathway
por: Saito, Yuichiro, et al.
Publicado: (2014)

Heterodimerization of the human RNase P/MRP subunits Rpp20 and Rpp25 is a prerequisite for interaction with the P3 arm of RNase MRP RNA
por: Hands-Taylor, Katherine L. D., et al.
Publicado: (2010)

Targeted CRISPR disruption reveals a role for RNase MRP RNA in human preribosomal RNA processing
por: Goldfarb, Katherine C., et al.
Publicado: (2017)

RNase MRP RNA and RNase P activity in plants are associated with a Pop1p containing complex
por: Krehan, Mario, et al.
Publicado: (2012)

Phosphorylation of hTERT at threonine 249 is a novel tumor biomarker of aggressive cancer with poor prognosis in multiple organs
por: Matsuda, Yoko, et al.
Publicado: (2022)

A disease-linked lncRNA mutation in RNase MRP inhibits ribosome synthesis
por: Robertson, Nic, et al.
Publicado: (2022)

hTERT mRNA dendritic cell vaccination: complete response in a pancreatic cancer patient associated with response against several hTERT epitopes
por: Suso, Else M. Inderberg, et al.
Publicado: (2011)

Characterization of RNase MRP RNA and novel snoRNAs from Giardia intestinalis and Trichomonas vaginalis
por: Chen, Xiaowei S, et al.
Publicado: (2011)

The mRNA expression of hTERT in human breast carcinomas correlates with VEGF expression
por: Kirkpatrick, Katharine L, et al.
Publicado: (2004)

MicroRNA-21 Regulates hTERT via PTEN in Hypertrophic Scar Fibroblasts
por: Zhu, Hua-Yu, et al.
Publicado: (2014)

A noncoding RNA gene on chromosome 10p15.3 may function upstream of hTERT
por: Miura, Norimasa, et al.
Publicado: (2009)

Interactions between subunits of Saccharomyces cerevisiae RNase MRP support a conserved eukaryotic RNase P/MRP architecture
por: Aspinall, Tanya V., et al.
Publicado: (2007)

siRNA suppression of hTERT using activatable cell-penetrating peptides in hepatoma cells
por: Li, Hua, et al.
Publicado: (2015)

PITX1 protein interacts with ZCCHC10 to regulate hTERT mRNA transcription
por: Ohira, Takahito, et al.
Publicado: (2019)

The Role of Alternative RNA Splicing in the Regulation of hTERT, Telomerase, and Telomeres: Implications for Cancer Therapeutics
por: Slusher, Aaron L., et al.
Publicado: (2020)

Modular architecture of eukaryotic RNase P and RNase MRP revealed by electron microscopy
por: Hipp, Katharina, et al.
Publicado: (2012)

Alternative Splicing of hTERT Pre-mRNA: A Potential Strategy for the Regulation of Telomerase Activity
por: Liu, Xuewen, et al.
Publicado: (2017)

MicroRNA-491-5p suppresses cervical cancer cell growth by targeting hTERT
por: Zhao, Qiang, et al.
Publicado: (2021)

ShRNA-mediated silencing of hTERT promote apoptosis and senescence in human ovarian cancer cells
por: Su, Chen, et al.
Publicado: (2019)

Antiretroviral treatment and expression of the mRNA levels for Pgp, MRP1, MRP4 and MRP5 in HIV antiretroviral naïve patients. Follow-up at 48 weeks
por: Falasca, Francesca, et al.
Publicado: (2010)

A Novel Model for the RNase MRP-Induced Switch between the Formation of Different Forms of 5.8S rRNA
por: Li, Xiao, et al.
Publicado: (2021)

Characterization of blood-derived exosomal hTERT mRNA as a biomarker for colon cancer and Lynch syndrome
por: Laish, Ido, et al.
Publicado: (2022)

Blood-Derived Exosomal hTERT mRNA in Patients with Lung Cancer: Characterization and Correlation with Response to Therapy
por: Rotem, Ofer, et al.
Publicado: (2023)

miR-19b regulates hTERT mRNA expression through targeting PITX1 mRNA in melanoma cells
por: Ohira, Takahito, et al.
Publicado: (2015)

An Improved Model for the hTERT Promoter Quadruplex
por: Chaires, Jonathan B., et al.
Publicado: (2014)

Cryo-EM structure of catalytic ribonucleoprotein complex RNase MRP
por: Perederina, Anna, et al.
Publicado: (2020)

Interferon Alpha on Expression of hTERT mRNA in Peripheral Blood Mononuclear Cells of Patients with Chronic Hepatitis B
por: Zhu, Chuan-wu, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_pksiikpn3lu92djfjesm8bkpqb