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Functions of MutLα, Replication Protein A (RPA), and HMGB1 in 5′-Directed Mismatch Repair
A purified system comprised of MutSα, MutLα, exonuclease 1 (Exo1), and replication protein A (RPA) (in the absence or presence of HMGB1) supports 5′-directed mismatch-provoked excision that terminates after mismatch removal. MutLα is not essential for this reaction but enhances excision termination,...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755878/ https://www.ncbi.nlm.nih.gov/pubmed/19515846 http://dx.doi.org/10.1074/jbc.M109.021287 |