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Functions of MutLα, Replication Protein A (RPA), and HMGB1 in 5′-Directed Mismatch Repair

A purified system comprised of MutSα, MutLα, exonuclease 1 (Exo1), and replication protein A (RPA) (in the absence or presence of HMGB1) supports 5′-directed mismatch-provoked excision that terminates after mismatch removal. MutLα is not essential for this reaction but enhances excision termination,...

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Detalles Bibliográficos
Autores principales:	Genschel, Jochen, Modrich, Paul
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2009
Materias:	DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755878/ https://www.ncbi.nlm.nih.gov/pubmed/19515846 http://dx.doi.org/10.1074/jbc.M109.021287

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