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A Human Embryonic Kidney 293T Cell Line Mutated at the Golgi α-Mannosidase II Locus

Disruption of Golgi α-mannosidase II activity can result in type II congenital dyserythropoietic anemia and induce lupus-like autoimmunity in mice. Here, we isolated a mutant human embryonic kidney (HEK) 293T cell line called Lec36, which displays sensitivity to ricin that lies between the parental...

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Detalles Bibliográficos
Autores principales: Crispin, Max, Chang, Veronica T., Harvey, David J., Dwek, Raymond A., Evans, Edward J., Stuart, David I., Jones, E. Yvonne, Lord, J. Michael, Spooner, Robert A., Davis, Simon J.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755891/
https://www.ncbi.nlm.nih.gov/pubmed/19465480
http://dx.doi.org/10.1074/jbc.M109.006254