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A Human Embryonic Kidney 293T Cell Line Mutated at the Golgi α-Mannosidase II Locus
Disruption of Golgi α-mannosidase II activity can result in type II congenital dyserythropoietic anemia and induce lupus-like autoimmunity in mice. Here, we isolated a mutant human embryonic kidney (HEK) 293T cell line called Lec36, which displays sensitivity to ricin that lies between the parental...
Autores principales: | Crispin, Max, Chang, Veronica T., Harvey, David J., Dwek, Raymond A., Evans, Edward J., Stuart, David I., Jones, E. Yvonne, Lord, J. Michael, Spooner, Robert A., Davis, Simon J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755891/ https://www.ncbi.nlm.nih.gov/pubmed/19465480 http://dx.doi.org/10.1074/jbc.M109.006254 |
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