Cargando…

Evaluation of triploid↔diploid and trisomy-3↔diploid mouse chimeras as models for investigating how lineage restriction occurs in confined placental mosaicism

Human confined placental mosaicism (CPM), where the placental trophoblast is mosaic for a chromosome abnormality but the fetus is chromosomally normal, can cause problems for prenatal diagnosis, but its causes are poorly understood. Tetraploid↔diploid chimeras provide a model for the development of...

Descripción completa

Detalles Bibliográficos
Autores principales: Everett, Clare A, Keighren, Margaret A, Flockhart, Jean H, West, John D
Formato: Texto
Lenguaje:English
Publicado: BioScientifica 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756007/
https://www.ncbi.nlm.nih.gov/pubmed/18042637
http://dx.doi.org/10.1530/REP-07-0285