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Critical role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis
Tissue macrophages comprise a heterogeneous group of cell types differing in location, surface markers and function1. Red pulp macrophages are a distinct splenic subset involved in removing senescent red blood cells2. Transcription factors such as PU.1 and C/EBPα play general roles in myelomonocytic...
Autores principales: | Kohyama, Masako, Ise, Wataru, Edelson, Brian T., Wilker, Peter R., Hildner, Kai, Mejia, Carlo, Frazier, William A., Murphy, Theresa L., Murphy, Kenneth M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756102/ https://www.ncbi.nlm.nih.gov/pubmed/19037245 http://dx.doi.org/10.1038/nature07472 |
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