Targeted inhibition of the Hedgehog pathway in established malignant glioma xenografts enhances survival

Hedgehog pathway activity has been demonstrated in malignant glioma. However, its role in tumor growth has not been determined. Here we demonstrate that pharmacological inhibition of the Hedgehog pathway in established orthotopic malignant glioma xenografts confers a survival advantage. Pathway inhi...

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Detalles Bibliográficos
Autores principales: Sarangi, A, Valadez, J G, Zieber, S, Abel, T W, Thompson, R C, Cooper, M K
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756306/
https://www.ncbi.nlm.nih.gov/pubmed/19617900
http://dx.doi.org/10.1038/onc.2009.208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756306/
https://www.ncbi.nlm.nih.gov/pubmed/19617900
http://dx.doi.org/10.1038/onc.2009.208

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