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Targeted inhibition of the Hedgehog pathway in established malignant glioma xenografts enhances survival
Hedgehog pathway activity has been demonstrated in malignant glioma. However, its role in tumor growth has not been determined. Here we demonstrate that pharmacological inhibition of the Hedgehog pathway in established orthotopic malignant glioma xenografts confers a survival advantage. Pathway inhi...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756306/ https://www.ncbi.nlm.nih.gov/pubmed/19617900 http://dx.doi.org/10.1038/onc.2009.208 |