The Tumor Microenvironment: The Making of a Paradigm

What has been will be again, what has been done will be done again; there is nothing new under the sun (Ecclesiastes 1:9) Stephen Paget was the conceptual father of the role played by the Tumor Microenvironment (TME) in tumor progression. The focus of this essay is the developmental phase of the pos...

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Detalles Bibliográficos
Autor principal: Witz, Isaac P.
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2009
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756342/
https://www.ncbi.nlm.nih.gov/pubmed/19701697
http://dx.doi.org/10.1007/s12307-009-0025-8
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author Witz, Isaac P.
author_facet Witz, Isaac P.
author_sort Witz, Isaac P.
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description What has been will be again, what has been done will be done again; there is nothing new under the sun (Ecclesiastes 1:9) Stephen Paget was the conceptual father of the role played by the Tumor Microenvironment (TME) in tumor progression. The focus of this essay is the developmental phase of the post Paget TME research. Attempts will be made to highlight some of the pioneering work of scientists from the late sixties through the eighties of last century who laid the foundations for the contemporary scientific achievements of TME research but whose ground breaking studies are rarely cited. This review should serve as a small tribute to their great work.
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spelling pubmed-27563422009-10-07 The Tumor Microenvironment: The Making of a Paradigm Witz, Isaac P. Cancer Microenviron Original Paper What has been will be again, what has been done will be done again; there is nothing new under the sun (Ecclesiastes 1:9) Stephen Paget was the conceptual father of the role played by the Tumor Microenvironment (TME) in tumor progression. The focus of this essay is the developmental phase of the post Paget TME research. Attempts will be made to highlight some of the pioneering work of scientists from the late sixties through the eighties of last century who laid the foundations for the contemporary scientific achievements of TME research but whose ground breaking studies are rarely cited. This review should serve as a small tribute to their great work. Springer Netherlands 2009-08-23 /pmc/articles/PMC2756342/ /pubmed/19701697 http://dx.doi.org/10.1007/s12307-009-0025-8 Text en © The Author(s) 2009 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Original Paper
Witz, Isaac P.
The Tumor Microenvironment: The Making of a Paradigm
title The Tumor Microenvironment: The Making of a Paradigm
title_full The Tumor Microenvironment: The Making of a Paradigm
title_fullStr The Tumor Microenvironment: The Making of a Paradigm
title_full_unstemmed The Tumor Microenvironment: The Making of a Paradigm
title_short The Tumor Microenvironment: The Making of a Paradigm
title_sort tumor microenvironment: the making of a paradigm
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756342/
https://www.ncbi.nlm.nih.gov/pubmed/19701697
http://dx.doi.org/10.1007/s12307-009-0025-8
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